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Pharm Ther (2017) 42:676711

This bias inhibits receptor internalization, leading to prolonged efficacy and possibly improved tolerability

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These effects were more noticeable in longer trials and when ALA was combined with dietary changes.29 A 2020 dose-response meta-analysis confirmed small but statistically significant reductions in weight and BMI across 18+ randomized controlled trials.30 However, waist circumference (WC) a marker of central obesity showed no consistent change, and the benefit appeared greater in women and with longer treatment durations

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The West nomogram in Figure 12-1 allows the user to plot the estimated square meters of BSA by using height and weight measurements