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Circulation, 104(16), 1985-1991

Brazil: Demand for GLP-1 companion products in Brazil is projected to grow at around an 11.8% CAGR through 2036, supported by expanding GLP-1 user base for obesity management and diabetes care, and growing demand for high-quality and convenient companion product formats such as sachets, bars, and liquid shots

Even further, a 2020 meta-analysis found a significant reduction of body weight associated with berberine intake

Tirzepatide , originally developed for type 2 diabetes, works as a dual agonist targeting the GIP and GLP-1 receptors, both of which are integral to appetite control, insulin regulation, and energy balancekey factors in effective weight management