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Meanwhile, government-sponsored plans like Medicare generally do not cover weight-loss drugs

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Mazdutide reduced liver fat by 80% in participants with elevated baseline levels

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- Use an acid (such as trifluoroacetic acid) or base (such as n-butylamine) to disconnect the polypeptide chain from the solid support

The authors highlighted the diverse, but significant, ways the 4,000+ patients responded to the medication: 88% of participants lost 5% of body weight or more