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doi: 10.3389/fonc.2018.00520 122 HrdinaJBanningAKippALohGBlautMBrigelius-FlohR

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

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Three primary forms of autophagy, macroautophagy, microautophagy, and molecular chaperone-mediated autophagy, are mediated by lysosomes, which are important organelles for the breakdown of proteins (Mizushima and Levine, 2020)

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Animal data indicates rapid clearance typical of unmodified small peptides, generally minutes to low hours in plasma