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Phase 3 Retatrutide trials currently underway will address these gaps with larger, longer studies before FDA submission

For patients with obesity, metabolic disorders, or poor blood sugar control, the drug has been showing promising results in reducing starting weight and improving insulin sensitivity

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For imputation, the package mice (v 3.13.0) was used

The SELECT trial, which evaluated semaglutide 2.4 mg against placebo for cardiovascular outcomes in patients with overweight and obesity without type 2 diabetes, showed significant decreases in total cholesterol, LDL-C, and triglycerides and an increase in HDL-C at 39.8 months [48]

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