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Previdi S, Maroni P, Matteucci E, Broggini M, Bendinelli P, Desiderio MA

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Among 84 patients with EGFR wild-type, high c-MET-expressing non-squamous NSCLC, the objective response rate (ORR) was 35% (95% CI: 2446), and the median duration of response (mDOR) was 7.2 months (95% CI: 4.212) [9]

Interaction with H1/3 revealed 14 docking solutions at site 5, the DNA-binding domain, where the peptide bound with a minimum energy of 56.49 kcal/mol using the sequence His-Pro-Ser-Tyr-Met-Ala-His-Pro-Ala-Arg-Lys

At 250 mcg twice daily, a single vial lasts approximately 10 days