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doi: 10.3389/fncel.2025.1601366 Received 27 March 2025 Accepted 10 June 2025 Published 04 July 2025 Volume 19 - 2025 Edited by Marco Cambiaghi, University of Verona, Italy Reviewed by Enoch Luis, National Council of Science and Technology (CONACYT), Mexico Mingzi Zhang, University of Southern California, United States Updates Copyright 2025 Bessetti and Litwa

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NNMT is expressed most highly in human liver (RPKM 188.3), followed by the appendix (RPKM 69.3) and approximately ten other tissues, with a biased expression pattern

Others find that staying hydrated and eating smaller portions for several hours post-injection minimizes gastrointestinal discomfort, especially during dose escalation phases when sensitivity is higher

Omega-3 fatty acids help modulate inflammation

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