Secreted frizzled-related protein 2 ameliorates diabetic cardiomyopathy by activating mitophagy
doi: 10.1038/nrdp.2016.57 159 JohamAEPiltonenTLujanMEKiconcoSTayCT
While it may resemble melasma or dark spots, it is actually a type of acquired dermal pigmentation, not a true dark spot
Figure 6 7 Mental health disorders in cirrhosis 7.1 Prevalence and characteristics Mental health disorders leading to poor quality of life and emotional distress profoundly impact patients with cirrhosis, leading to increasing severity of symptoms related to liver disease, advanced histological abnormalities, increased mortality rates, and poor adherence to medical treatments (40)
Curcumin could also significantly inhibit cell cycle progression in G0/G1-S phase and increase the number of cells in the G0/G1 phase, downregulating the Bcl-2, CDK4, and cyclin D1 protein expression in cells and tissues [55]
I., Raquib, R., Shafer, P