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This is done by the CYP 2D6 microsomal enzyme of which there are 5-6 pharmogenetically active forms ranging from ultra-slow to ultra-fast

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Krzywanski DM, Dickinson DA, Iles KE, Wigley AF, Franklin CC, Liu RM, et al

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Similarly, knocking out augmenter of liver regeneration (ALR) promotes macrophage activation and ferroptosis by altering carnitine palmitoyltransferase 1A ( CPT1A )-dependent lipid metabolism (Zhang et al., 2024a)