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379 This suggests that the redox modification of MICU3 may finely regulate mitochondrial calcium influx, consequently modulating the progression of human diseases

Regulatory exclusivity periods include five-year new chemical entity (NCE) exclusivity for first-in-class small molecules, three-year clinical investigation exclusivity for new formulations, seven-year orphan drug exclusivity for treatments targeting rare diseases, and six months of pediatric exclusivity attached to existing patents when sponsors conduct FDA-requested pediatric studies [3]

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