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Microdosing approaches exist across medicine, from immunotherapy using gradual exposure to psychiatric medications starting below therapeutic doses to assess tolerance

Reported side effects from supplements After week 4 and 8, participants reported by questionnaire whether they tolerated the supplement, supplementation protocol, and reported any medical problems/symptoms they encountered throughout the duration of the study

MyHMB is generally well-tolerated with minimal side effects at standard doses

Anesth Analg 136(4):628635

Synthetic antioxidants Synthetic antioxidants have been developed to have a standard antioxidant activity measurement system and to compare with natural antioxidants that are incorporated into food

Hydration and Dehydration: Alcohols Dehydrating Effect: One of the primary effects of alcohol is its dehydrating impact on the body