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A study suggests that long-term intake of -carotene, retinol, and lutein nutritional supplements alone to prevent diseases, especially in patients with underlying conditions and smokers, is not recommended

Weaker circadian signals mean fragmented sleep, difficulty falling asleep, reduced slow-wave sleep, and impaired REM cycles

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Hypersensitivity reactions, including anaphylaxis, have been reported as well

For the published science and laboratory handling, see our BPC-157 research guide