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Mounting data reveal intimate Nrf2NLRP3 crosstalk: Nrf2 activation limits the transcriptional priming of NLRP3, curtails mitochondrial ROS, and directly interferes with inflammasome assembly, whereas unchecked NLRP3 signaling feeds forward to inhibit Nrf2 and perpetuate oxidative damage (sciencedirect.com)

Mayo Clinic Proceedings: Innovations, Quality & Outcomes

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Inflammation Research , 57(5), 205210