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Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice

The targeted fat reduction caused by Tesamorelin can ease the strain on internal organs and reduce inflammation, both of which are critical for metabolic health

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doi: 10.1155/2016/7432797

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Given the HDX technique's success detecting GLP-1R peptide ligand interactions we decided to explore its use as a robust approach for ligand screening to validate the ability of proposed small molecule ligands to bind the extracellular domain of GLP-1R