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Subsequently, the cells were sub-cultured into CTT media devoid of copper but containing 200 M of the copper chelator bathocuproinedisulfonic acid (BCS, Sigma-Aldrich, St

STAT proteins contain six domains, including an N-terminal domain, coiled coil domain, DNA-binding domain, linker domain, SH2 domain, and transactivation domain (98)

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In addition, there was no significant linear relationship between dose (g/day) (coefficients = 0.02, p = 0.600) and duration of intervention (weeks) (coefficients = 0.54, p = 0.578) and changes in insulin (Figures 6B, 7B)

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There are two compartment-specific BCAA transaminases in humans, BCAT1 (or cBCAT), which is located in the cytoplasm and primarily expressed in the brain, and BCAT2 (or mBCAT), which is located in mitochondria with ubiquitous expression