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Most researchers calculate backward: first choose the dose in micrograms, then determine how much solvent yields a convenient concentration

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Characterization of the biophysical properties of the mutated channels and their response to sympathetic activity has helped to identify the importance of EADs and sympathetic stimulation as proarrhythmic triggers, providing the scientific basis for beta-blocker therapy (or left cardiac sympathetic denervation) as a mainstay of antiarrhythmic therapy in LQTS [29]

Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, et al