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2022;7(19):e159863
Keep it pretty steady without too many ups and downs
In newer phase 3 trials, researchers used doses like 2 mg, 4 mg, 6 mg, 9 mg, and 12 mg, still taken once a week and increased slowly over time
Both substantially outperform semaglutide's 15%
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One study with more than 300 participants saw a 15.8% decrease in body weight for semaglutide after 68 weeks.3 Another study saw a 12.4% decrease after 72 weeks.4 Averaging those two outcomes, someone weighing 200 pounds could reasonably expect to lose around 14% of their body weight after about 16 months
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