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3.2.2 Downregulate expressions of cyclooxygenase-2 and inducible nitric oxide synthase Overexpression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) are correlated to colorectal carcinogenesis, and inhibition of their activities leads to cancer prevention (Sheehan et al., 1999

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Oberli MA, Schoellhammer CM, Langer R, Blankschtein D

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