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However, they tend to heal slowly due to several factors: limited blood supply compared to muscle tissue repetitive mechanical stress during daily activity disruption of collagen fibers gradual degeneration over time inflammation that interferes with tissue repair Because tendons rely heavily on collagen for strength and flexibility, healing often depends on rebuilding organized collagen fibers within the tissue

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NOS inhibitors, for example, NG-monomethyl-L-arginine (L-NMMA), and asymmetrical dimethylarginine, can both improve insulin sensitivity (124, 125)