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Authored by Carter Hensley, CPC, MedSole RCM.

This drug blocks enzymes called Janus kinases (JAKs), which is thought to result in suppression of the pro-inflammatory action of several interleukins, including interleukin-6 (IL-6) (Migita 2014

79, 86, 87 This might be due to the predominance of the AT 1 receptor over the AT 2 receptor expression in blood vessels

Taken together, results from these trials showed that more patients treated with Bimzelx saw at least a 50% improvement in the signs and symptoms of hidradenitis suppurativa at 16 weeks, as compared with placebo

others discontinue due to nausea or side effects

The solution may still appear clear, but its potency could be reduced by an unknown amount