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To assess the impact of post-randomization changes in metformin use, two sensitivity analyses were conducted for the CV outcomes: (1) censoring for initiation and discontinuation of metformin during the study using the Cox proportional hazards model described above

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Experiencing a crash may be a more salient or distinct subjective experience to patients than the gradual return of ADHD symptoms, which may influence reporting

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Commercially available therapeutic lapidated GLP-1 analogues, semaglutide and liraglutide, have the significant advantage of prolonged in vivo half-lives (hours to days) compared to native GLP-1, which degrades within minutes