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doi: 10.1111/JTH.15191 97 PrasannanNHeightmanMHillmanTWallEBellRKesslerAet al

The catalytic activity of the molecule was suggested to be, at least partially, involved (since insulin signaling was improved following inclusion of a DPP-4 inhibitor), but the DPP-4 substrate(s) mediating the effect were not identified

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Beyond the scale, participants treated with semaglutide also experienced improvements in cardiometabolic markers, including waist circumference, A1C, triglycerides, and liver enzyme levels