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A 170-pound person on GLP-1 medications needs approximately 93 grams of protein daily to preserve muscle (1.2g per kg body weight)

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Therefore, premature discontinuation of oral semaglutide may be due to the fact that elderly patients may be weaker, prefer treatment once a week, and are more susceptible to gastrointestinal intolerance (Newton, 2005) combined with baseline comorbidities that complicate continuation of treatment

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More than half 166 died from accidental overdoses

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