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The canonical nuclear factor kappa-B (NF-B) pathway in microglia is a critical regulator of inflammation and drives the M1 phenotype (Anilkumar and Wright-Jin, 2024)

Based on these results, semaglutide is expected to be submitted to FDA for MASH in 2025, potentially becoming the first GLP-1 RA officially approved for MASH

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10 weight loss clinics prescribing GLP-1 medications in Gilbert accept health insurance