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Specifically, HC induced a significant change in 15 proteins (i.e., 9 and 6 up- and down-regulated, respectively) involved in autophagy, including the down-regulation of NPC1 (Nieman-Pick type C) and QSOX1 (quiescin sulfhydryl oxidase 1) and the up-regulation of HMOX1 (heme oxygenase 1) and KDM4A (lysine demethylase 4A)

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A recent study in healthy, normal-weight men treated with dulaglutide for 4 weeks found no negative effect on testosterone, libido, or sperm parameters compared to placebofrontiersin.org

This is why manufacturers often recommend storing the vials in a cool, dark place