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Reporting summary Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article
Key Takeaways: NAC is converted to glutathione inside cells, with 70% stability during digestion
STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity
Persistent IL-2 stimulation in CD8 + T cells leads to chronic activation of STAT5, which leads to the expression of tryptophan hydroxylase 1 [201]
Another strategy outlined below relies on inhibition of the xCT system, which mediates the entry of cystine that fuels the trans-sulphuration pathway
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