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This is consistent with previously-characterized clade II TyrA enzymes from -proteobacteria and fungi, which also preferred PDH over ADH activity (Mannhaupt et al., 1989

IGF1 can induce the expression and accumulation of BNIP3 in mitochondria through a PI3K-dependent manner, indicating that IGF1 promotes mitophagy in vitro (Lyons et al., 2017)

The subunit differs in its amino acid sequence from other gonadotropins and is hCG-specific