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The most common polymorphisms of GSTM1-1 and GSTT1-1 gene loci consist in the complete deletion of the genes

This section consolidates the pathological consequences of zinc dysregulation by systematically linking compartment-specific molecular mechanisms to their associated clinical manifestations, as summarized in Table 2

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Compared to PDCs with high expression of VRK2, PDCs with low expression of VRK2 displayed a higher basal level of ROS and a lower basal level of GSH