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Nat Rev Endocrinol 21 , 6566 (2025)

The combination of redox buffering and inflammatory damping is a recurring theme across the compound's reported applications

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Methods We combined data from several Swedish Registers and identified patients with incident type 2 diabetes being treated with GLP-1 RAs between 2006 and 2015, and matched them to diabetic patients who did not use GLP-1 RAs as the comparisons

Despite its growing popularity among athletes and its wide availability through non-regulated sources, there is minimal human data available. Vasireddi et al., American Journal of Sports Medicine, 2025 This gap matters