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Segev, MD, PhD

A practical periconception management approach is as follows: (i) Target achievement: Continue treatment alongside lifestyle intervention until pre-specified weight and metabolic targets are met (e.g., 5%10% weight loss with improvement in IR markers)

As with any nutrient, individual results differ from one person to the next

Albayram O, Herbert MK, Kondo A, Tsai CY, Baxley S, et al