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10.1016/j.tins.2024.04.003 41 ZoltanU.StefanoT.TamasK.WrenJ
Furthermore, an interventional clinical trial revealed recently the amelioration of AAC was not followed by an increase or decrease in the sKlotho level in MHD patients with secondary hyperparathyroidism, which further challenged the clinical value of sKlotho in VC (Chou et al., 2019) The inconsistent studies were summarized and the average score was 6.6 stars, as shown in Table 4
This heptapeptide, derived from the naturally occurring human tetrapeptide Tuftsin, has been shown to possess a wide range of biological activities, including enhancing memory, reducing anxiety, and potentially mitigating the effects of neurodegenerative diseases
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Overt hepatic encephalopathy was recognized by the detection of marker symptoms, such as disorientation and flapping tremor, because of their excellent interobserver reliability 2,3
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