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For example, with reference to the clinical ocular trials mentioned in Sosne and Kleinman, the researchers noted that no long-term safety studies have been done with TI34 treatment in the eye for more than a month

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However, they do not affect opiate receptor activity nor do they alter levels of other pituitary hormones

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Patient safety and effective medical care hinge significantly on following established medical protocols and guidelines

Guo et al., 2022