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No interaction between grapefruit and Ozempic (semaglutide) is expected, and none is listed in the MHRA Summary of Product Characteristics (SmPC) or British National Formulary (BNF)

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For example, the STEP 3 randomized clinical trial associated semaglutide 2.4 mg combined with intensive behavioral therapy (i.e., 30 counseling visits) (258)

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Prior authorization may be required to ensure that the medication is medically necessary for the individuals weight management needs