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This study was stopped early due to the frequency and magnitude of the elevation in ALT in the treatment group relative to controls, although none of the participants expressed symptoms of liver disease

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Personal and family medical history: Be sure to disclose if you have a history of medical conditions like pancreatitis, diabetic retinopathy, gallbladder disease, kidney disease, or thyroid cancer

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After combining the amounts measured for the known FXR-antagonistic BAs, we also showed that the percentage of T(/)MCA, (T/G)UDCA, and (T)HDCA in the gallbladder bile was significantly increased in MMI + T3-5d mice compared to MMI mice (Fig