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Conservative care is almost always the starting point: activity modification, overthecounter medications, and early physical therapy

Additionally, we confirm that all aspects of the study are reported in accordance with the ARRIVE guidelines to ensure high-quality and transparent reporting of animal research

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Best practice is to maintain consistent refrigeration without repeated temperature excursions

Treatment of Obesity with GLP-1RAs GLP-1RAs enhance satiety, decrease food consumption, and delay gastric emptying, while also promoting insulin secretion and suppressing glucagon release in a glucose-dependent manner.92,93 Subcutaneous administration of liraglutide (3 mg daily) and semaglutide (2.4 mg weekly) has been approved for obesity management