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The effect of l-Carnitine on the attenuated autophagic flux induced by PFOS was further evaluated using an additional CQ treatment

LIRA did not significantly alter soluble guanylyl cyclase or endothelial nitric oxide synthase (eNOS) mRNA levels, nor total myocardial eNOS protein expression

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This injury is potentially mediated via pro-inflammatory cytokines, particularly TNF-alpha and IL-1beta [69]