Novo puts $285m into monthly GLP-1 based on Ascendis tech Novo Nordisk has partnered with Ascendis Pharma on less frequently dosed drugs for obesity and other metabolic diseases, starting with a once-monthly GLP-1 receptor agonist
Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve
Epithalon (Epitalon) Primary uses: Longevity Telomere lengthening Sleep regulation (melatonin) Anti-aging Typical dosing: 10mg per cycle 1mg daily for 10 days Cycles: Every 3-6 months Administration: Subcutaneous injection Special notes: Strong evidence for telomere lengthening Used in anti-aging protocols Well-tolerated Improves sleep regulation (pineal gland function) Thymosin Alpha-1 Primary uses: Immune system optimization Anti-viral effects Longevity Chronic illness support Typical dosing: 0.5-1mg, 2-3 times per week Duration: Ongoing or cycles Administration: Subcutaneous injection Special notes: Powerful immune modulator FDA-approved for hepatitis (Zadaxin) Well-studied safety profile Used in longevity protocols Selank Primary uses: Anxiety reduction Cognitive enhancement Immune modulation Neuroprotection Typical dosing: 250-500mcg daily Injectable or intranasal Duration: 2-4 weeks, then break Administration: Subcutaneous injection or intranasal spray Special notes: Developed in Russia Anxiolytic without sedation Improves focus and mental clarity No dependence or withdrawal Semax Primary uses: Cognitive enhancement Focus and concentration Neuroprotection Stroke recovery Typical dosing: 300-600mcg daily Injectable or intranasal Duration: 2-4 weeks, then break Administration: Subcutaneous injection or intranasal spray Special notes: Powerful nootropic Increases BDNF (brain-derived neurotrophic factor) Improves learning and memory Developed in Russia Sexual health peptides These enhance libido, arousal, and sexual function
doi: 10.1016/j.critrevonc.2024.104349, 61
Refer to our guide on how long semaglutide takes to work for realistic timeline expectations
GLUT-4 is responsible for glucose transport into adipocytes in response to insulin stimulation
