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The principal intestinal bacteria implicated in bile acid metabolism include Bacteroides , Clostridium , Lactobacillus , Bifidobacterium , and Ruminococcus

Rescue at the DNA Level Gene therapy encompasses techniques that can alter the expression of an organisms genes by targeting the DNA either through transgene delivery, or by direct modification of the genome, with the goal of therapeutically restoring a pathologically expressed gene to normal expression levels [38]

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Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease

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The disease begins with restlessness, anger, and sleep disturbances