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[PMC free article: PMC3161301] [PubMed: 21775755] (Among 460 patients with diabetic polyneuropathy treated with ALA [600 mg] or placebo once daily for 4 years, there were no differences in the primary outcomes between the two treatment groups while severe adverse events were more frequent with ALA [38% vs 28%]
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(2014) Structure of a eukaryotic thiaminase I
Pros: Alta dosificacin (3000 mg diarios)
Biochemical and Biophysical Research Communications 440:336341
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