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perhaps wariness about adding another long-term medication

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New combinations and oral GLP-1 options The field of GLP-1 therapies is rapidly evolving, with exciting developments that enhance convenience and efficacy

Most patients experience: Mild to moderate appetite reduction Some gastrointestinal effects (nausea, occasional diarrhea or constipation) Early changes in food preferences and portion sizes Minimal weight loss (13 lbs is typical during the first month) Months 23 (5 mg 7.5 mg) As the dose increases, appetite suppression becomes more pronounced

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The Benoist 2014 study used the HGF/MET dimerization antagonist Hinge to block Dihexas procognitive activity in scopolamine-impaired rats, with oral Dihexa (2 mg/kg/day) reversing the scopolamine-induced Morris water maze deficit when administered alone but losing effect when co-administered with Hinge [3]