doi: 10.1038/s41392-020-00428-9 16 FengHStockwellBR
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Analysis of transcriptome and metabolome profiles alterations in fatty liver induced by high-fat diet in rat
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In contrast, probiotic intervention antagonizes ferroptosis through mechanisms such as reducing inflammation, repairing intestinal barrier, releasing antimicrobial peptides (cAMPs), regulating iron overload, and inhibiting lipid peroxidation (182, 183), thereby ameliorating the pathological phenotype of IBD ( Figure 3 )
Among the drugs in the pipeline are ampakines, which target a type of glutamate receptor in the brain