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While short term implementation of ketogenic diets has shown potential in several neurodegenerative diseases for improving metabolic function and producing neuroprotective and anti-inflammatory intermediates [99], long-term implementation is limited by decreased patient adherence and occasional adverse cardiac, renal and cognitive events (particularly in pediatric patients) [100]
A 5% false discovery rate (FDR) was used to determine significant differential changes
Laboratory investigations have explored its interactions with hypothalamic and limbic receptor systems, as well as its potential modulatory effects on stress hormone pathways in preclinical settings
Semaglutide acts on brain appetite centers , helping patients feel fuller for longer, which supports both glycemic control and weight reduction
doi: 10.1007/s00401-012-0954-z 21 BakanSKayadibiYErsenEVatankuluBUstundagNHaslogluZI
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