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Microarray analysis has identified GHR as one of the top eight genes upregulated by BPC-157, with a 2.29-fold increase in expression

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Animal studies administering 5-Amino-1MQ orally to diet-induced obese mice have shown dose-dependent reductions in body weight (typically 10-30% reduction compared to vehicle-treated obese controls over 4-12 week treatment periods), with the weight loss primarily reflecting fat mass reduction while lean mass is preserved or even increased

2.2 Pharmacokinetic studies of BPC157 in beagle dogs Our proposed clinical dose of BPC157 was 200 g/person/day, and its equivalent dose in dogs was 6 g/kg (converted based on body surface area)