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Our focus was on mapping existing research, identifying trends, and discussing potential directions for further studies

Further studies in obese non-diabetic models have also identified renoprotection with GLP-1 receptor agonists (71), thus stimulating investigations into a potential clinical role for such agents in obesity-associated kidney disease in the absence of overt diabetes, as indicated below

Many users find this dose sufficient and may not need to increase further

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In addition, GLP-1 therapies appear to promote natriuresis, or increased sodium excretion, through effects on the kidneys