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The relative changes in gene expression were calculated using the 2 Ct (cycle threshold) quantification method, normalized to expression levels of the Rplp0 (Ribosomal protein, large, P0)

Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice

Recent evidence links IBD to altered O-glycan expression in the mucus layer, including increased levels of short-chain O-glycans and modified terminal structures

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doi: 10.1016/j.ajpath.2015.06.019

As a result, c-MYC induced reprogramming of mitochondrial metabolism by diverting glucose away from the TCA cycle and leaving cells susceptible to glutamine addiction to sustain anaplerosis