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Baele, M

Manipulation of intracellular GSH pools by supplementation with GSH precursors was found to block induction of JNK activity by methylating agents [26] Similarly p53 function has been reported to be redox sensitive, primarily through in vitro modification of its cysteine residues [27]

Peptide Classification: Synthetic copper-binding tripeptide

Therefore, the ratio of oxidised and reduced glutathione indicates the redox state of a cell and may represent a valuable tool for the assessment of oxidative stress and a target for drug-based antioxidant therapies [4]

Copper inhibits -amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion

The distinction between a systemic and a localized route matters more than it might appear