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While initial clinical observations indicate promising effects in specific conditions such as diabetic peripheral neuropathy, irritable bowel syndrome, and idiopathic intracranial hypertension, rigorous clinical trials are needed to confirm their efficacy, elucidate weight-loss-independent mechanisms, and establish comprehensive safety profiles across various pain conditions

5.8.2.4 Platinum salts Nonspecific and specific bronchial hyperresponsiveness in immediate-type asthma caused by platinum salts did not cease after removal from exposure (Merget et al., 1994) (see also section 4.3.4.1)

1a), broadly matching the scRNA-seq stages (Supplementary Table 1)

Although complex pathogenesis undoubtedly contributes to ovarian aging, increasing attention is being paid to the extensive influence of oxidative stress