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The cagrilintide with tirzepatide combination targets appetite and satiety through multiple mechanisms but does not include the direct fat-cell targeting that AOD 9604 provides

Do not administer this drug to the following patients: 1) Patients with hypersensitivity to the components of this drug 2) Patients with hypercalcemia, hypercalciuria 3) Patients with calcium oxalate stones 4) Patients with renal impair 5) Patients who are immobilized in a hospital bed 6) Sarcoidosis 7) Patients with pseudoparathyroidism 3

The question is what is driving the symptoms and what type of care is safest and most appropriate

The longest animal safety studies extended to 6 weeks of repeated dosing