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[41] : 975 Children diagnosed with low serum B 12 can be treated with intramuscular injections, then transitioned to an oral dietary supplement

Its strong safety profile and effective absorption make it suitable for a wide range of patients, including those with poor dietary intake, malabsorption issues, or conditions affecting intrinsic factor

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However, Vitamin B12 supports normal energy metabolism, and people with low B12 levels may feel more supported after addressing a deficiency or insufficiency

The presence of funnel plot asymmetry also suggests potential publication bias, which warrants further scrutiny