systematic review of 13 studies encompassing 84,065 patients demonstrated significantly higher retained gastric contents rates (odds ratio 5.56, 95% confidence interval 3.359.23) but found no significant difference in actual aspiration rates (odds ratio 1.75, 95% confidence interval 0.644.77) [37]
Following GLP-1 deprescription, patients weight did not significantly increase at 6 or 12 months post deprescription, compared to many well-known drug trials (in red) where patients regain up to two thirds of weight loss after discontinuing the drug
Scand J Public Health 39:7274
What is Tomato Powder
& Mahoney, E
While sommarutide is undoubtedly an exciting potential treatment option, there is still a lack of clear clinical data on the mechanism of action of GLP-1 agonists in NASH, such as whether GLP-1 agonists have a direct, independent role in improving NASH, or simply by improving body weight, insulin resistance, and so on